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peaceful places to stay in New Mexico
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Best Airbnb in Los Ranchos NM

Welcome to SantuaRio Grande, our Big River Sanctuary nestled in the tranquil landscapes of Los Ranchos de Albuquerque, New Mexico.

As a one-of-a-kind destination in the area, we offer a wellness infused haven for peace, providing a retreat for rejuvenation and relaxation.

Our property is designed with your well-being in mind, offering a range of amenities and experiences to nourish your body, mind, and soul. Sit in tranquility on the back porch of the main house overlooking our French garden. SantuaRio Grande is dedicated to providing a holistic approach to your stay with meditation spaces, holistic wellness, yoga offerings and space to just be. 

Immerse yourself in our serene surroundings, where the gentle rustle of leaves, the sounds of the flowing water fountain and the sweet chirpings of visiting local birds create an atmosphere of calm and renewal. Whether you're enjoying a leisurely stroll around the property or unwinding with a restorative massage, every moment at SantuaRio Grande is designed to promote your relaxation.

Our individually designed and unique accommodations are mindfully curated to enhance your comfort and relaxation. Features such as luxurious bed linens, crisp white towels, fireplaces and thoughtful decor are inspired by the natural beauty of the Southwest. Wake up refreshed and revitalized each morning, ready to start your day with a sense of balance and tranquility.

Add on our extra offerings like nourishing balanced meals made with fresh herbs from our property. Have a customized facial or bodywork session with master professionals from the wellness industry.

Enjoy a Bliss Night created for, and catered to, your family or group. For those who want to dive deeper, therapeutic mind/body, heart-centered, integrated council sessions are available. We also offer the ideal relaxing location and accommodations for private, small group, family, or professional retreats. Reach out to us today and let us design your unique get away!

At Santuario Grande we invite you to embark on a journey of wellness and rejuvenation. Let us be your oasis of serenity in Los Ranchos, where you can escape the stresses of daily life and reconnect with your truest self.

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Healing retreats in New Mexico
When health is absent, wisdom cannot reveal itself, art cannot manifest, strength cannot fight, wealth becomes useless, and intelligence cannot be applied.”   
Herophilus 330-260 BC 



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The Main house, inspired by Albuquerque’s old Alvarado Hotel train station, offers another part of the Sanctuary for our guests to enjoy. Your Hosts reside here, with their private quarters located on the upper level. The lower level houses the Therapy room & Yoga floor, along with other amenities, and is open to our guests from 8am to 8pm.

  • ​​A Porch area where guests may take in the morning sunshine and meet other travelers while relaxing with a favorite beverage

  • Kitchen boasts large island for gathering around

  • Dining room area with a table, which seats 8+The Kitchen/Dining room area is available for guests' use and may be reserved for larger meal prep if your group is lodging with us

  • Coffee and Teas available

  • Ice machine provides ice for your units' needs

  • Outdoor shared grill available for use upon request

  • Living Room with oversized couch and multiple sittings areas

  • Board Games available for use during your visit

  • Puzzle table

  • Yoga floor for stretching and light workout (mats provided)

  • Walking paths throughout the 1+acre property

  • Disc golf basket for a little putting practice

  • Cornhole 

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You'll be enchanted by the stylish and inviting ambiance of our cozy freestanding studio, nestled among the lush surroundings of Santuario Grande Bed & Breakfast. This charming retreat is one of two separate buildings discreetly tucked behind the main house, offering a serene escape from the hustle and bustle of everyday life.

As you step into this intimate space, you'll immediately be greeted by thoughtfully curated decor that blends modern comforts with rustic charm. The interior exudes warmth and character, featuring rich wooden accents, plush furnishings, and tasteful artistic touches that create an atmosphere of understated elegance.

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Step into the quintessential New Mexico Casita, where every detail is meticulously crafted to offer a truly enchanting retreat. This charming abode epitomizes the essence of Southwestern hospitality, providing the perfect blend of rustic charm and luxurious comfort.

From the moment you enter, you'll be captivated by the thoughtful touches that adorn this regal sanctuary. Rich hues inspired by the desert landscape adorn the walls, complemented by handcrafted furnishings and traditional accents that evoke a sense of timeless elegance.

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For those seeking a fun and spacious converted space on a budget, we've got you covered. Our 600 sq.ft studio offers all the essentials needed to enjoy Santuario Grande and experience everything Albuquerque has to offer, whether you're here for work or play.

Featuring high ceilings that create a grand feeling, our studio provides a comfortable and inviting environment for guests. Whether you're unwinding after a day of exploring or simply relaxing, our studio serves as the perfect home base for your adventures.

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Our most adored and remarkable building, recognized in the Village of Los Ranchos de Albuquerque since the late 90’s. The architecture harkens back to John Gaw Meem’s iconic New Mexico churches and boasts an amazing 3-tiered, dragonfly adorned, stained glass chandelier.


The marvelous woodwork is matched only by the flawless custom-built spiral stairs leading to one of the lofts. The opposing loft has a soaking tub and Juliet balcony. We have no doubt that this unique casa is the perfect space for family or best friends to relax and enjoy, make lifelong memories, while spending time together in the Land of Enchantment.


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